Use "tranquillize|tranquillized|tranquillizes|tranquillizing" in a sentence

1. Synonyms for Calming include soothing, relaxing, sedative, tranquillizing, tranquilizing, comforting, lulling, narcotic, pacifying and restful

2. During pharmacological studies on the tranquillizing drug 1-(2-hydroxyethyl)-4,3-(2-chloro-10-phenothiazil)-propylpiperazine (perphenazine), a considerable adrenolytic activity of this substance has been demonstrated.